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Structural basis of a public antibody response to SARS-CoV-2

Molecular-level understanding of human neutralizing antibody responses to SARS-CoV-2 could accelerate vaccine design and facilitate drug discovery. We analyzed 294 SARS-CoV-2 antibodies and found that IGHV3–53 is the most frequently used IGHV gene for targeting the receptor binding domain (RBD) of t...

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Detalles Bibliográficos
Autores principales: Yuan, Meng, Liu, Hejun, Wu, Nicholas C., Lee, Chang-Chun D., Zhu, Xueyong, Zhao, Fangzhu, Huang, Deli, Yu, Wenli, Hua, Yuanzi, Tien, Henry, Rogers, Thomas F., Landais, Elise, Sok, Devin, Jardine, Joseph G., Burton, Dennis R., Wilson, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302194/
https://www.ncbi.nlm.nih.gov/pubmed/32577642
http://dx.doi.org/10.1101/2020.06.08.141267