SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins.

Tightly packed complexes of nucleocapsid protein and genomic RNA form the core of viruses and may assemble within viral factories, dynamic compartments formed within the host cells. Here, we examine the possibility that the multivalent RNA-binding nucleocapsid protein (N) from the severe acute respi...

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Detalles Bibliográficos
Autores principales: Perdikari, Theodora Myrto, Murthy, Anastasia C., Ryan, Veronica H., Watters, Scott, Naik, Mandar T., Fawzi, Nicolas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302208/
https://www.ncbi.nlm.nih.gov/pubmed/32577653
http://dx.doi.org/10.1101/2020.06.09.141101

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