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Landscape and Selection of Vaccine Epitopes in SARS-CoV-2

There is an urgent need for a vaccine with efficacy against SARS-CoV-2. We hypothesize that peptide vaccines containing epitope regions optimized for concurrent B cell, CD4(+) T cell, and CD8(+) T cell stimulation would drive both humoral and cellular immunity with high specificity, potentially avoi...

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Detalles Bibliográficos
Autores principales: Smith, Christof C., Entwistle, Sarah, Willis, Caryn, Vensko, Steven, Beck, Wolfgang, Garness, Jason, Sambade, Maria, Routh, Eric, Olsen, Kelly, Kodysh, Julia, O’Donnell, Timothy, Haber, Carsten, Heiss, Kirsten, Stadler, Volker, Garrison, Erik, Grant, Oliver C., Woods, Robert J., Heise, Mark, Vincent, Benjamin G., Rubinsteyn, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302209/
https://www.ncbi.nlm.nih.gov/pubmed/32577654
http://dx.doi.org/10.1101/2020.06.04.135004