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Containment of future waves of COVID-19: simulating the impact of different policies and testing capacities for contact tracing, testing, and isolation
We used multi-agent simulations to estimate the testing capacity required to find and isolate a number of infections sufficient to break the chain of transmission of SARS-CoV-2. Depending on the mitigation policies in place, a daily capacity between 0.7 to 3.6 tests per thousand was required to cont...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302294/ https://www.ncbi.nlm.nih.gov/pubmed/32577688 http://dx.doi.org/10.1101/2020.06.05.20123372 |
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author | Fiore, Vincenzo G. DeFelice, Nicholas Glicksberg, Benjamin S. Perl, Ofer Shuster, Anastasia Kulkarni, Kaustubh O’Brien, Madeline Pisauro, M. Andrea Chung, Dongil Gu, Xiaosi |
author_facet | Fiore, Vincenzo G. DeFelice, Nicholas Glicksberg, Benjamin S. Perl, Ofer Shuster, Anastasia Kulkarni, Kaustubh O’Brien, Madeline Pisauro, M. Andrea Chung, Dongil Gu, Xiaosi |
author_sort | Fiore, Vincenzo G. |
collection | PubMed |
description | We used multi-agent simulations to estimate the testing capacity required to find and isolate a number of infections sufficient to break the chain of transmission of SARS-CoV-2. Depending on the mitigation policies in place, a daily capacity between 0.7 to 3.6 tests per thousand was required to contain the disease. However, if contact tracing and testing efficacy dropped below 60% (e.g. due to false negatives or reduced tracing capability), the number of infections kept growing exponentially, irrespective of any testing capacity. Under these conditions, the population’s geographical distribution and travel behaviour could inform sampling policies to aid a successful containment. |
format | Online Article Text |
id | pubmed-7302294 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cold Spring Harbor Laboratory |
record_format | MEDLINE/PubMed |
spelling | pubmed-73022942020-06-23 Containment of future waves of COVID-19: simulating the impact of different policies and testing capacities for contact tracing, testing, and isolation Fiore, Vincenzo G. DeFelice, Nicholas Glicksberg, Benjamin S. Perl, Ofer Shuster, Anastasia Kulkarni, Kaustubh O’Brien, Madeline Pisauro, M. Andrea Chung, Dongil Gu, Xiaosi medRxiv Article We used multi-agent simulations to estimate the testing capacity required to find and isolate a number of infections sufficient to break the chain of transmission of SARS-CoV-2. Depending on the mitigation policies in place, a daily capacity between 0.7 to 3.6 tests per thousand was required to contain the disease. However, if contact tracing and testing efficacy dropped below 60% (e.g. due to false negatives or reduced tracing capability), the number of infections kept growing exponentially, irrespective of any testing capacity. Under these conditions, the population’s geographical distribution and travel behaviour could inform sampling policies to aid a successful containment. Cold Spring Harbor Laboratory 2020-06-07 /pmc/articles/PMC7302294/ /pubmed/32577688 http://dx.doi.org/10.1101/2020.06.05.20123372 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/It is made available under a CC-BY-NC-ND 4.0 International license (http://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Article Fiore, Vincenzo G. DeFelice, Nicholas Glicksberg, Benjamin S. Perl, Ofer Shuster, Anastasia Kulkarni, Kaustubh O’Brien, Madeline Pisauro, M. Andrea Chung, Dongil Gu, Xiaosi Containment of future waves of COVID-19: simulating the impact of different policies and testing capacities for contact tracing, testing, and isolation |
title | Containment of future waves of COVID-19: simulating the impact of different policies and testing capacities for contact tracing, testing, and isolation |
title_full | Containment of future waves of COVID-19: simulating the impact of different policies and testing capacities for contact tracing, testing, and isolation |
title_fullStr | Containment of future waves of COVID-19: simulating the impact of different policies and testing capacities for contact tracing, testing, and isolation |
title_full_unstemmed | Containment of future waves of COVID-19: simulating the impact of different policies and testing capacities for contact tracing, testing, and isolation |
title_short | Containment of future waves of COVID-19: simulating the impact of different policies and testing capacities for contact tracing, testing, and isolation |
title_sort | containment of future waves of covid-19: simulating the impact of different policies and testing capacities for contact tracing, testing, and isolation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302294/ https://www.ncbi.nlm.nih.gov/pubmed/32577688 http://dx.doi.org/10.1101/2020.06.05.20123372 |
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