G6PD variant distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19

Chloroquine/hydroxychloroquine have been proposed as potential treatments for COVID-19. These drugs have warning labels for use in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Analysis of whole-genome sequence data of 458 individuals from sub-Saharan Africa showed significan...

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Detalles Bibliográficos
Autores principales: da Rocha, Jorge, Othman, Houcemeddine, Tiemessen, Caroline T., Botha, Gerrit, Ramsay, Michèle, Masimirembwa, Collen, Adebamowo, Clement, Choudhury, Ananyo, Brandenburg, Jean-Tristan, Matshaba, Mogomotsi, Simo, Gustave, Gamo, Francisco-Javier, Hazelhurst, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302299/
https://www.ncbi.nlm.nih.gov/pubmed/32577690
http://dx.doi.org/10.1101/2020.05.27.20114066

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