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Semicarbazide-sensitive amine oxidase inhibition ameliorates albuminuria and glomerulosclerosis but does not improve tubulointerstitial fibrosis in diabetic nephropathy

Semicarbazide-sensitive amine oxidase (SSAO) is an enzyme with a unique dual function in controlling inflammation as well as reactive oxygen species (ROS) generation. We have demonstrated benefit of SSAO inhibition in acute kidney fibrosis. However the function of SSAO in chronic kidney disease (CKD...

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Detalles Bibliográficos
Autores principales:	Wong, May YW, Saad, Sonia, Wong, Muh Geot, Stangenberg, Stefanie, Jarolimek, Wolfgang, Schilter, Heidi, Zaky, Amgad, Gill, Anthony, Pollock, Carol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302447/ https://www.ncbi.nlm.nih.gov/pubmed/32555665 http://dx.doi.org/10.1371/journal.pone.0234617

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