Cargando…
KD-64—A new selective A(2A) adenosine receptor antagonist has anti-inflammatory activity but contrary to the non-selective antagonist—Caffeine does not reduce diet-induced obesity in mice
The A(2) adenosine receptors play an important role, among others, in the regulation of inflammatory process and glucose homeostasis in diabetes and obesity. Thus, the presented project evaluated of influence of the selective antagonist of A(2A) adenosine receptor—KD-64 as compared to the known non-...
Autores principales: | Kotańska, Magdalena, Dziubina, Anna, Szafarz, Małgorzata, Mika, Kamil, Reguła, Karolina, Bednarski, Marek, Zygmunt, Małgorzata, Drabczyńska, Anna, Sapa, Jacek, Kieć-Kononowicz, Katarzyna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302451/ https://www.ncbi.nlm.nih.gov/pubmed/32555600 http://dx.doi.org/10.1371/journal.pone.0229806 |
Ejemplares similares
-
Preliminary Evidence of the Potent and Selective Adenosine A2B Receptor Antagonist PSB-603 in Reducing Obesity and Some of Its Associated Metabolic Disorders in Mice
por: Kotańska, Magdalena, et al.
Publicado: (2022) -
The GPR18 Agonist PSB-KD-107 Exerts Endothelium-Dependent Vasorelaxant Effects
por: Kotańska, Magdalena, et al.
Publicado: (2021) -
Effects of GPR18 Ligands on Body Weight and Metabolic Parameters in a Female Rat Model of Excessive Eating
por: Kotańska, Magdalena, et al.
Publicado: (2021) -
Evaluation of Some Safety Parameters of Dual Histamine H(3) and Sigma-2 Receptor Ligands with Anti-Obesity Potential
por: Mika, Kamil, et al.
Publicado: (2023) -
Manifestations of Liver Impairment and the Effects of MH-76, a Non-Quinazoline α1-Adrenoceptor Antagonist, and Prazosin on Liver Tissue in Fructose-Induced Metabolic Syndrome
por: Kubacka, Monika, et al.
Publicado: (2023)