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PD173074 blocks G1/S transition via CUL3-mediated ubiquitin protease in HepG2 and Hep3B cells

Fibroblast growth factor receptors (FGFRs) are frequently altered in a variety of human cancer cells and are overexpressed in hepatocellular carcinoma (HCC). Several literatures have proven that they are efficacious for HCC therapy, however, the underlying mechanism remains unclear. Here, we found F...

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Detalles Bibliográficos
Autores principales: Qiao, Chuchu, Qian, Hongyan, Wang, Jue, Zhao, Tingting, Ma, Pengyu, Wang, Sicen, Zhang, Tao, Liu, Xinshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302471/
https://www.ncbi.nlm.nih.gov/pubmed/32555680
http://dx.doi.org/10.1371/journal.pone.0234708