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PD173074 blocks G1/S transition via CUL3-mediated ubiquitin protease in HepG2 and Hep3B cells
Fibroblast growth factor receptors (FGFRs) are frequently altered in a variety of human cancer cells and are overexpressed in hepatocellular carcinoma (HCC). Several literatures have proven that they are efficacious for HCC therapy, however, the underlying mechanism remains unclear. Here, we found F...
Autores principales: | Qiao, Chuchu, Qian, Hongyan, Wang, Jue, Zhao, Tingting, Ma, Pengyu, Wang, Sicen, Zhang, Tao, Liu, Xinshe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302471/ https://www.ncbi.nlm.nih.gov/pubmed/32555680 http://dx.doi.org/10.1371/journal.pone.0234708 |
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