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BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline
Current microbiome applications require substantial bioinformatics expertise to execute. As microbiome clinical diagnostics are being developed, there is a critical need to implement computational tools and applications that are user-friendly for the medical community to understand microbiome correl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302521/ https://www.ncbi.nlm.nih.gov/pubmed/32555605 http://dx.doi.org/10.1371/journal.pone.0234860 |
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author | Shamsaddini, Amirhossein Dadkhah, Kimia Gillevet, Patrick M. |
author_facet | Shamsaddini, Amirhossein Dadkhah, Kimia Gillevet, Patrick M. |
author_sort | Shamsaddini, Amirhossein |
collection | PubMed |
description | Current microbiome applications require substantial bioinformatics expertise to execute. As microbiome clinical diagnostics are being developed, there is a critical need to implement computational tools and applications that are user-friendly for the medical community to understand microbiome correlation with the health. To address this need, we have developed BiomMiner (pronounced as “biominer”), an automated pipeline that provides a comprehensive analysis of microbiome data. The pipeline finds taxonomic signatures of microbiome data and compiles actionable clinical report that allows clinicians and biomedical scientists to efficiently perform statistical analysis and data mining on the large microbiome datasets. BiomMiner generates web-enabled visualization of the analysis results and is specifically designed to facilitate the use of microbiome datasets in clinical applications. |
format | Online Article Text |
id | pubmed-7302521 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-73025212020-06-19 BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline Shamsaddini, Amirhossein Dadkhah, Kimia Gillevet, Patrick M. PLoS One Research Article Current microbiome applications require substantial bioinformatics expertise to execute. As microbiome clinical diagnostics are being developed, there is a critical need to implement computational tools and applications that are user-friendly for the medical community to understand microbiome correlation with the health. To address this need, we have developed BiomMiner (pronounced as “biominer”), an automated pipeline that provides a comprehensive analysis of microbiome data. The pipeline finds taxonomic signatures of microbiome data and compiles actionable clinical report that allows clinicians and biomedical scientists to efficiently perform statistical analysis and data mining on the large microbiome datasets. BiomMiner generates web-enabled visualization of the analysis results and is specifically designed to facilitate the use of microbiome datasets in clinical applications. Public Library of Science 2020-06-18 /pmc/articles/PMC7302521/ /pubmed/32555605 http://dx.doi.org/10.1371/journal.pone.0234860 Text en © 2020 Shamsaddini et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Shamsaddini, Amirhossein Dadkhah, Kimia Gillevet, Patrick M. BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline |
title | BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline |
title_full | BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline |
title_fullStr | BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline |
title_full_unstemmed | BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline |
title_short | BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline |
title_sort | biomminer: an advanced exploratory microbiome analysis and visualization pipeline |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302521/ https://www.ncbi.nlm.nih.gov/pubmed/32555605 http://dx.doi.org/10.1371/journal.pone.0234860 |
work_keys_str_mv | AT shamsaddiniamirhossein biommineranadvancedexploratorymicrobiomeanalysisandvisualizationpipeline AT dadkhahkimia biommineranadvancedexploratorymicrobiomeanalysisandvisualizationpipeline AT gillevetpatrickm biommineranadvancedexploratorymicrobiomeanalysisandvisualizationpipeline |