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BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline

Current microbiome applications require substantial bioinformatics expertise to execute. As microbiome clinical diagnostics are being developed, there is a critical need to implement computational tools and applications that are user-friendly for the medical community to understand microbiome correl...

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Detalles Bibliográficos
Autores principales: Shamsaddini, Amirhossein, Dadkhah, Kimia, Gillevet, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302521/
https://www.ncbi.nlm.nih.gov/pubmed/32555605
http://dx.doi.org/10.1371/journal.pone.0234860
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author Shamsaddini, Amirhossein
Dadkhah, Kimia
Gillevet, Patrick M.
author_facet Shamsaddini, Amirhossein
Dadkhah, Kimia
Gillevet, Patrick M.
author_sort Shamsaddini, Amirhossein
collection PubMed
description Current microbiome applications require substantial bioinformatics expertise to execute. As microbiome clinical diagnostics are being developed, there is a critical need to implement computational tools and applications that are user-friendly for the medical community to understand microbiome correlation with the health. To address this need, we have developed BiomMiner (pronounced as “biominer”), an automated pipeline that provides a comprehensive analysis of microbiome data. The pipeline finds taxonomic signatures of microbiome data and compiles actionable clinical report that allows clinicians and biomedical scientists to efficiently perform statistical analysis and data mining on the large microbiome datasets. BiomMiner generates web-enabled visualization of the analysis results and is specifically designed to facilitate the use of microbiome datasets in clinical applications.
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spelling pubmed-73025212020-06-19 BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline Shamsaddini, Amirhossein Dadkhah, Kimia Gillevet, Patrick M. PLoS One Research Article Current microbiome applications require substantial bioinformatics expertise to execute. As microbiome clinical diagnostics are being developed, there is a critical need to implement computational tools and applications that are user-friendly for the medical community to understand microbiome correlation with the health. To address this need, we have developed BiomMiner (pronounced as “biominer”), an automated pipeline that provides a comprehensive analysis of microbiome data. The pipeline finds taxonomic signatures of microbiome data and compiles actionable clinical report that allows clinicians and biomedical scientists to efficiently perform statistical analysis and data mining on the large microbiome datasets. BiomMiner generates web-enabled visualization of the analysis results and is specifically designed to facilitate the use of microbiome datasets in clinical applications. Public Library of Science 2020-06-18 /pmc/articles/PMC7302521/ /pubmed/32555605 http://dx.doi.org/10.1371/journal.pone.0234860 Text en © 2020 Shamsaddini et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Shamsaddini, Amirhossein
Dadkhah, Kimia
Gillevet, Patrick M.
BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline
title BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline
title_full BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline
title_fullStr BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline
title_full_unstemmed BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline
title_short BiomMiner: An advanced exploratory microbiome analysis and visualization pipeline
title_sort biomminer: an advanced exploratory microbiome analysis and visualization pipeline
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302521/
https://www.ncbi.nlm.nih.gov/pubmed/32555605
http://dx.doi.org/10.1371/journal.pone.0234860
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