Efficacy of intra-articular polynucleotides associated with hyaluronic acid vs hyaluronic acid alone in the treatment of knee osteoarthritis: A systematic review and meta-analysis of randomized clinical trial

BACKGROUND: The reduced range of motion and pain are the most characteristic clinical features of osteoarthritis (OA). Hyaluronic acid (HA), which is one of the infiltrative therapies for OA treatment, and polynucleotides (PNs), which is a DNA-derived macromolecule favored cell growth and collagen p...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Lei, Ningbo, Chang, Ruilong, Yang, Chenxu, Li, Qiang, Zuo, Ning, Gu, Yubiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
6900
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302631/
https://www.ncbi.nlm.nih.gov/pubmed/32541518
http://dx.doi.org/10.1097/MD.0000000000020689

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