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Virus subtype-specific suppression of MAVS aggregation and activation by PB1-F2 protein of influenza A (H7N9) virus

Human infection with avian influenza A (H5N1) and (H7N9) viruses causes severe respiratory diseases. PB1-F2 protein is a critical virulence factor that suppresses early type I interferon response, but the mechanism of its action in relation to high pathogenicity is not well understood. Here we show...

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Detalles Bibliográficos
Autores principales:	Cheung, Pak-Hin Hinson, Lee, Tak-Wang Terence, Kew, Chun, Chen, Honglin, Yuen, Kwok-Yung, Chan, Chi-Ping, Jin, Dong-Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302872/ https://www.ncbi.nlm.nih.gov/pubmed/32511263 http://dx.doi.org/10.1371/journal.ppat.1008611

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