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The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
Cancer/testis (CT) antigens are proteins whose expression is normally restricted to germ cells yet aberrantly activated in tumors, where their functions remain relatively cryptic. Here we report that ZNF165, a CT antigen frequently expressed in triple-negative breast cancer (TNBC), associates with S...
Autores principales: | Gibbs, Zane A, Reza, Luis C, Cheng, Chun-Chun, Westcott, Jill M, McGlynn, Kathleen, Whitehurst, Angelique W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302877/ https://www.ncbi.nlm.nih.gov/pubmed/32515734 http://dx.doi.org/10.7554/eLife.57679 |
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