Cholinergic neuroplasticity in asthma driven by TrkB signaling

Parasympathetic neurons in the airways control bronchomotor tone. Increased activity of cholinergic neurons are mediators of airway hyperresponsiveness (AHR) in asthma, however, mechanisms are not elucidated. We describe remodeling of the cholinergic neuronal network in asthmatic airways driven by b...

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Detalles Bibliográficos
Autores principales: Dragunas, Guilherme, Woest, Manon E., Nijboer, Susan, Bos, Sophie T., van Asselt, Janet, de Groot, Anne P., Vohlídalová, Eva, Vermeulen, Corneel J., Ditz, Benedikt, Vonk, Judith M., Koppelman, Gerard H., van den Berge, Maarten, ten Hacken, Nick H. T., Timens, Wim, Munhoz, Carolina D., Prakash, Y. S., Gosens, Reinoud, Kistemaker, Loes E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302963/
https://www.ncbi.nlm.nih.gov/pubmed/32277855
http://dx.doi.org/10.1096/fj.202000170R

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