Upregulated immuno-modulator PD-L1 in malignant peripheral nerve sheath tumors provides a potential biomarker and a therapeutic target

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are rare aggressive sarcomas with poor prognosis. More than half of MPNSTs develop from benign precursor tumors associated with neurofibromatosis type 1 (NF1) which is a tumor suppressor gene disorder. Early detection of malignant transfo...

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Detalles Bibliográficos
Autores principales: Farschtschi, Said, Kluwe, Lan, Park, Su-Jin, Oh, Su-Jun, Mah, Nancy, Mautner, Victor-Felix, Kurtz, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303069/
https://www.ncbi.nlm.nih.gov/pubmed/32193699
http://dx.doi.org/10.1007/s00262-020-02548-1

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