Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples

Genome-wide, polygenic risk scores (PRS) have emerged as a useful way to characterize genetic liability. There is growing evidence that PRS may prove useful for early identification of those at increased risk for certain diseases. The current potential of PRS for alcohol use disorders (AUD) remains...

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Detalles Bibliográficos
Autores principales: Barr, Peter B., Ksinan, Albert, Su, Jinni, Johnson, Emma C., Meyers, Jacquelyn L., Wetherill, Leah, Latvala, Antti, Aliev, Fazil, Chan, Grace, Kuperman, Samuel, Nurnberger, John, Kamarajan, Chella, Anokhin, Andrey, Agrawal, Arpana, Rose, Richard J., Edenberg, Howard J., Schuckit, Marc, Kaprio, Jaakko, Dick, Danielle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303212/
https://www.ncbi.nlm.nih.gov/pubmed/32555147
http://dx.doi.org/10.1038/s41398-020-00865-8

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