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Phosphoregulated orthogonal signal transduction in mammalian cells

Orthogonal tools for controlling protein function by post-translational modifications open up new possibilities for protein circuit engineering in synthetic biology. Phosphoregulation is a key mechanism of signal processing in all kingdoms of life, but tools to control the involved processes are ver...

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Detalles Bibliográficos
Autores principales: Scheller, Leo, Schmollack, Marc, Bertschi, Adrian, Mansouri, Maysam, Saxena, Pratik, Fussenegger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303213/
https://www.ncbi.nlm.nih.gov/pubmed/32555187
http://dx.doi.org/10.1038/s41467-020-16895-1