Cargando…

NORAD orchestrates endometrial cancer progression by sequestering FUBP1 nuclear localization to promote cell apoptosis

Long noncoding RNAs (lncRNAs) are emerging as critical regulators in tumor initiation and progression. However, the biological mechanisms and potential clinical application of lncRNA NORAD in endometrial cancer (EC) remain unknown. Herein, we identified NORAD underwent promoter hypermethylation-asso...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Tong, Wu, Yukang, Hu, Xiang, Chen, Yaqi, Jia, Wenwen, He, Qizhi, Bian, Yiding, Wang, Mengfei, Guo, Xudong, Kang, Jiuhong, Wan, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303217/ https://www.ncbi.nlm.nih.gov/pubmed/32555178 http://dx.doi.org/10.1038/s41419-020-2674-y

Ejemplares similares

Cmarr/miR-540-3p axis promotes cardiomyocyte maturation transition by orchestrating Dtna expression
por: Wu, Yukang, et al.
Publicado: (2022)

FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC expression in primary single murine cells
por: Zheng, Ying, et al.
Publicado: (2020)

Aging well with Norad
por: Marques, Filipa Carvalhal, et al.
Publicado: (2019)

Collagen triple helix repeat containing 1 promotes endometrial cancer cell migration by activating the focal adhesion kinase signaling pathway
por: Hu, Xiang, et al.
Publicado: (2020)

Phenotyping of immune and endometrial epithelial cells in endometrial carcinomas revealed by single-cell RNA sequencing
por: Guo, Yu-e, et al.
Publicado: (2021)

The Low Endometrial Expression of Long Non-Coding RNA NORAD Is Associated with Recurrent Pregnancy Losses and Unexplained Infertility
por: Huang, Ying, et al.
Publicado: (2022)

FUSE binding protein FUBP3 is a potent regulator in Japanese encephalitis virus infection
por: Xu, Peng, et al.
Publicado: (2021)

Cpmer: A new conserved eEF1A2-binding partner that regulates Eomes translation and cardiomyocyte differentiation
por: Lyu, Yao, et al.
Publicado: (2022)

FUBP1: a new protagonist in splicing regulation of the DMD gene
por: Miro, Julie, et al.
Publicado: (2015)

Multiple Functions of Fubp1 in Cell Cycle Progression and Cell Survival
por: Kang, Mingyu, et al.
Publicado: (2020)

Retracted: The Low Endometrial Expression of Long Non-Coding RNA NORAD Is Associated with Recurrent Pregnancy Losses and Unexplained Infertility
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

LncRNA NORAD defects deteriorate the formation of age-related macular degeneration
por: Zhang, Jinfeng, et al.
Publicado: (2023)

FUS is sequestered in nuclear aggregates in ALS patient fibroblasts
por: Schwartz, Jacob C., et al.
Publicado: (2014)

Diagnostic implications of lncRNA NORAD in breast cancer
por: Zhang, Yaping, et al.
Publicado: (2023)

Endometrial regeneration with endometrial epithelium: homologous orchestration with endometrial stroma as a feeder
por: Yokomizo, Ryo, et al.
Publicado: (2021)

Developmental Roles of FUSE Binding Protein 1 (Fubp1) in Tooth Morphogenesis
por: Aryal, Yam Prasad, et al.
Publicado: (2020)

Knockdown of SLCO4C1 inhibits cell proliferation and metastasis in endometrial cancer through inactivating the PI3K/Akt signaling pathway
por: Hu, Xiang, et al.
Publicado: (2020)

TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer
por: Yang, BiKang, et al.
Publicado: (2021)

PUMILIO hyperactivity drives premature aging of Norad-deficient mice
por: Kopp, Florian, et al.
Publicado: (2019)

Comparative structural analyses and nucleotide-binding characterization of the four KH domains of FUBP1
por: Ni, Xiaomin, et al.
Publicado: (2020)

FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon
por: Dong, Sujie, et al.
Publicado: (2022)

SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA
por: Tichon, Ailone, et al.
Publicado: (2018)

FUBP3 interacts with FGF9 3′ microsatellite and positively regulates FGF9 translation
por: Gau, Bing-Huang, et al.
Publicado: (2011)

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
por: Jiao, Yuchen, et al.
Publicado: (2012)

Fangchinoline suppresses conjunctival melanoma by directly binding FUBP2 and inhibiting the homologous recombination pathway
por: Bao, Keting, et al.
Publicado: (2021)

FUBP1 mediates the growth and metastasis through TGFβ/Smad signaling in pancreatic adenocarcinoma
por: Zhang, Yue, et al.
Publicado: (2021)

Endometrial Tumors with MSI-H and dMMR Share a Similar Tumor Immune Microenvironment
por: Song, Yunfeng, et al.
Publicado: (2021)

PAUPAR and PAX6 sequentially regulate human embryonic stem cell cortical differentiation
por: Xu, Yanxin, et al.
Publicado: (2021)

Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis
por: Bian, Weihua, et al.
Publicado: (2020)

Delayed Mesoderm and Erythroid Differentiation of Murine Embryonic Stem Cells in the Absence of the Transcriptional Regulator FUBP1
por: Wesely, Josephine, et al.
Publicado: (2017)

Differentially Expressed Long Noncoding RNAs Involved in FUBP1 Promoting Hepatocellular Carcinoma Cells Proliferation
por: Li, Xianpeng, et al.
Publicado: (2021)

Autophagy orchestrates adaptive responses to targeted therapy in endometrial cancer
por: Eritja, Núria, et al.
Publicado: (2017)

PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD
por: Elguindy, Mahmoud M, et al.
Publicado: (2019)

Overexpression of long noncoding RNA NORAD in colorectal cancer associates with tumor progression
por: Wang, Lili, et al.
Publicado: (2018)

The Potential of NORAD–PUMILIO–RALGAPB Regulatory Axis as a Biomarker in Breast Cancer
por: Muller, Cristiane Sato Mara, et al.
Publicado: (2022)

Active Caspases and Cleaved Cytokeratins Are Sequestered into Cytoplasmic Inclusions in Trail-Induced Apoptosis
por: MacFarlane, Marion, et al.
Publicado: (2000)

LncRNA NORAD Promotes Proliferation And Inhibits Apoptosis Of Gastric Cancer By Regulating miR-214/Akt/mTOR Axis
por: Tao, Wei, et al.
Publicado: (2019)

Autocrine motility factor promotes endometrial cancer progression by targeting GPER-1
por: Li, Yiran, et al.
Publicado: (2019)

FUBP1 promotes neuroblastoma proliferation via enhancing glycolysis-a new possible marker of malignancy for neuroblastoma
por: Jiang, Ping, et al.
Publicado: (2019)

RTL1 promotes melanoma proliferation by regulating Wnt/β-catenin signalling
por: Fan, Guobiao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_h5acslaudka85tnrrmnafjrkfs