Gastric Neuroendocrine Carcinoma with Rapid Progression

As gastric neuroendocrine carcinoma (NEC) is a rapidly growing cancer, most cases are diagnosed at advanced stages. We herein report a 74-year-old woman with an early-stage gastric NEC whose history included endoscopic submucosal dissection treatment for three early-stage gastric cancer lesions five...

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Detalles Bibliográficos
Autores principales: Iwamoto, Maho, Gotoda, Takuji, Noda, Yasuhiro, Esaki, Mitsuru, Moriyama, Mitsuhiko, Yoshida, Nao, Takayama, Tadatoshi, Kobayashi, Hiroko, Masuda, Shinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303455/
https://www.ncbi.nlm.nih.gov/pubmed/32074574
http://dx.doi.org/10.2169/internalmedicine.3961-19
Descripción
Sumario:As gastric neuroendocrine carcinoma (NEC) is a rapidly growing cancer, most cases are diagnosed at advanced stages. We herein report a 74-year-old woman with an early-stage gastric NEC whose history included endoscopic submucosal dissection treatment for three early-stage gastric cancer lesions five years prior to the current presentation. We also describe the changes observed over time. An endoscopic examination during follow-up revealed an NEC (measuring 6 mm) in the gastric vestibule, for which distal gastrectomy was performed. Four months before surgery, the carcinoma exhibited specific morphological changes and lymphovascular invasion (despite the tumor being stage 1), suggesting a high-grade NEC.

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