A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease

Chronic kidney disease (CKD) poses a great burden to global public health as current therapies are generally ineffective. Early detection and effective therapy are crucial for the future prevention and progression of CKD. Nanoparticles (NPs) vary by particle size, charge, shape and the density of ta...

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Detalles Bibliográficos
Autores principales: Ma, Yanhong, Cai, Fanghao, Li, Yangyang, Chen, Jianghua, Han, Fei, Lin, Weiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303522/
https://www.ncbi.nlm.nih.gov/pubmed/32596555
http://dx.doi.org/10.1016/j.bioactmat.2020.05.002
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author Ma, Yanhong
Cai, Fanghao
Li, Yangyang
Chen, Jianghua
Han, Fei
Lin, Weiqiang
author_facet Ma, Yanhong
Cai, Fanghao
Li, Yangyang
Chen, Jianghua
Han, Fei
Lin, Weiqiang
author_sort Ma, Yanhong
collection PubMed
description Chronic kidney disease (CKD) poses a great burden to global public health as current therapies are generally ineffective. Early detection and effective therapy are crucial for the future prevention and progression of CKD. Nanoparticles (NPs) vary by particle size, charge, shape and the density of targeting ligands and are associated with enhancement of the pharmacokinetic properties, targetability, or the bioavailability of drugs. Thus, the emergence of NPs in medicine has provided novel solutions to the potential diagnosis and treatment of CKD. This review describes the current experimental research, clinical applications of NPs, the current challenges, and upcoming opportunities in the diagnosis and treatment of CKD.
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spelling pubmed-73035222020-06-25 A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease Ma, Yanhong Cai, Fanghao Li, Yangyang Chen, Jianghua Han, Fei Lin, Weiqiang Bioact Mater Article Chronic kidney disease (CKD) poses a great burden to global public health as current therapies are generally ineffective. Early detection and effective therapy are crucial for the future prevention and progression of CKD. Nanoparticles (NPs) vary by particle size, charge, shape and the density of targeting ligands and are associated with enhancement of the pharmacokinetic properties, targetability, or the bioavailability of drugs. Thus, the emergence of NPs in medicine has provided novel solutions to the potential diagnosis and treatment of CKD. This review describes the current experimental research, clinical applications of NPs, the current challenges, and upcoming opportunities in the diagnosis and treatment of CKD. KeAi Publishing 2020-06-15 /pmc/articles/PMC7303522/ /pubmed/32596555 http://dx.doi.org/10.1016/j.bioactmat.2020.05.002 Text en © 2020 [The Author/The Authors] http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Ma, Yanhong
Cai, Fanghao
Li, Yangyang
Chen, Jianghua
Han, Fei
Lin, Weiqiang
A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
title A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
title_full A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
title_fullStr A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
title_full_unstemmed A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
title_short A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
title_sort review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303522/
https://www.ncbi.nlm.nih.gov/pubmed/32596555
http://dx.doi.org/10.1016/j.bioactmat.2020.05.002
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