AGILE-ACCORD: A Randomized, Multicentre, Seamless, Adaptive Phase I/II Platform Study to Determine the Optimal Dose, Safety and Efficacy of Multiple Candidate Agents for the Treatment of COVID-19: A structured summary of a study protocol for a randomised platform trial

OBJECTIVES: Phase I - To determine the optimal dose of each candidate (or combination of candidates) entered into the platform. Phase II - To determine the efficacy and safety of each candidate entered into the platform, compared to the current Standard of Care (SoC), and recommend whether it should...

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Detalles Bibliográficos
Autores principales: Griffiths, Gareth, Fitzgerald, Richard, Jaki, Thomas, Corkhill, Andrea, Marwood, Ellice, Reynolds, Helen, Stanton, Louise, Ewings, Sean, Condie, Susannah, Wrixon, Emma, Norton, Andrea, Radford, Mike, Yeats, Sara, Robertson, Jane, Darby-Dowman, Rachel, Walker, Lauren, Khoo, Saye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303573/
https://www.ncbi.nlm.nih.gov/pubmed/32560744
http://dx.doi.org/10.1186/s13063-020-04473-1

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