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Influenza virus glycoprotein-reactive human monoclonal antibodies

Influenza continues to be a significant public health challenge. Two glycoproteins on the surface of influenza virus, hemagglutinin and neuraminidase, play a prominent role in the process of influenza virus infection and release. Monoclonal antibodies targeting glycoproteins can effectively prevent...

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Autores principales: Li, Yanbai, Wang, Lili, Si, Helong, Yu, Zhengsen, Tian, Shijun, Xiang, Rong, Deng, Xiaoqian, Liang, Ruiying, Jiang, Shibo, Yu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institut Pasteur. Published by Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303604/
https://www.ncbi.nlm.nih.gov/pubmed/32569735
http://dx.doi.org/10.1016/j.micinf.2020.06.003
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author Li, Yanbai
Wang, Lili
Si, Helong
Yu, Zhengsen
Tian, Shijun
Xiang, Rong
Deng, Xiaoqian
Liang, Ruiying
Jiang, Shibo
Yu, Fei
author_facet Li, Yanbai
Wang, Lili
Si, Helong
Yu, Zhengsen
Tian, Shijun
Xiang, Rong
Deng, Xiaoqian
Liang, Ruiying
Jiang, Shibo
Yu, Fei
author_sort Li, Yanbai
collection PubMed
description Influenza continues to be a significant public health challenge. Two glycoproteins on the surface of influenza virus, hemagglutinin and neuraminidase, play a prominent role in the process of influenza virus infection and release. Monoclonal antibodies targeting glycoproteins can effectively prevent the spread of the virus. In this review, we summarized currently reported human monoclonal antibodies targeting glycoproteins of influenza A and B viruses.
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spelling pubmed-73036042020-06-19 Influenza virus glycoprotein-reactive human monoclonal antibodies Li, Yanbai Wang, Lili Si, Helong Yu, Zhengsen Tian, Shijun Xiang, Rong Deng, Xiaoqian Liang, Ruiying Jiang, Shibo Yu, Fei Microbes Infect Article Influenza continues to be a significant public health challenge. Two glycoproteins on the surface of influenza virus, hemagglutinin and neuraminidase, play a prominent role in the process of influenza virus infection and release. Monoclonal antibodies targeting glycoproteins can effectively prevent the spread of the virus. In this review, we summarized currently reported human monoclonal antibodies targeting glycoproteins of influenza A and B viruses. Institut Pasteur. Published by Elsevier Masson SAS. 2020 2020-06-19 /pmc/articles/PMC7303604/ /pubmed/32569735 http://dx.doi.org/10.1016/j.micinf.2020.06.003 Text en © 2020 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Li, Yanbai
Wang, Lili
Si, Helong
Yu, Zhengsen
Tian, Shijun
Xiang, Rong
Deng, Xiaoqian
Liang, Ruiying
Jiang, Shibo
Yu, Fei
Influenza virus glycoprotein-reactive human monoclonal antibodies
title Influenza virus glycoprotein-reactive human monoclonal antibodies
title_full Influenza virus glycoprotein-reactive human monoclonal antibodies
title_fullStr Influenza virus glycoprotein-reactive human monoclonal antibodies
title_full_unstemmed Influenza virus glycoprotein-reactive human monoclonal antibodies
title_short Influenza virus glycoprotein-reactive human monoclonal antibodies
title_sort influenza virus glycoprotein-reactive human monoclonal antibodies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303604/
https://www.ncbi.nlm.nih.gov/pubmed/32569735
http://dx.doi.org/10.1016/j.micinf.2020.06.003
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