Strategies and perspectives to develop SARS-CoV-2 detection methods and diagnostics

To develop diagnostics and detection methods, current research is focussed on targeting the detection of coronavirus based on its RNA. Besides the RNA target, research reports are coming to develop diagnostics by targeting structure and other parts of coronavirus. PCR based detection system is widel...

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Autores principales: Jalandra, Rekha, Yadav, Amit K., Verma, Damini, Dalal, Nishu, Sharma, Minakshi, Singh, Rajeev, Kumar, Anil, Solanki, Pratima R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Masson SAS. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303646/
https://www.ncbi.nlm.nih.gov/pubmed/32768943
http://dx.doi.org/10.1016/j.biopha.2020.110446
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author Jalandra, Rekha
Yadav, Amit K.
Verma, Damini
Dalal, Nishu
Sharma, Minakshi
Singh, Rajeev
Kumar, Anil
Solanki, Pratima R.
author_facet Jalandra, Rekha
Yadav, Amit K.
Verma, Damini
Dalal, Nishu
Sharma, Minakshi
Singh, Rajeev
Kumar, Anil
Solanki, Pratima R.
author_sort Jalandra, Rekha
collection PubMed
description To develop diagnostics and detection methods, current research is focussed on targeting the detection of coronavirus based on its RNA. Besides the RNA target, research reports are coming to develop diagnostics by targeting structure and other parts of coronavirus. PCR based detection system is widely used and various improvements in the PCR based detection system can be seen in the recent research reports. This review will discuss multiple detection methods for coronavirus for developing appropriate, reliable, and fast alternative techniques. Considering the current scenario of COVID-19 diagnostics around the world and an urgent need for the development of reliable and cheap diagnostic, various techniques based on CRISPR technology, antibody, MIP, LAMP, microarray, etc. should be discussed and tried.
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spelling pubmed-73036462020-06-19 Strategies and perspectives to develop SARS-CoV-2 detection methods and diagnostics Jalandra, Rekha Yadav, Amit K. Verma, Damini Dalal, Nishu Sharma, Minakshi Singh, Rajeev Kumar, Anil Solanki, Pratima R. Biomed Pharmacother Article To develop diagnostics and detection methods, current research is focussed on targeting the detection of coronavirus based on its RNA. Besides the RNA target, research reports are coming to develop diagnostics by targeting structure and other parts of coronavirus. PCR based detection system is widely used and various improvements in the PCR based detection system can be seen in the recent research reports. This review will discuss multiple detection methods for coronavirus for developing appropriate, reliable, and fast alternative techniques. Considering the current scenario of COVID-19 diagnostics around the world and an urgent need for the development of reliable and cheap diagnostic, various techniques based on CRISPR technology, antibody, MIP, LAMP, microarray, etc. should be discussed and tried. Published by Elsevier Masson SAS. 2020-09 2020-06-19 /pmc/articles/PMC7303646/ /pubmed/32768943 http://dx.doi.org/10.1016/j.biopha.2020.110446 Text en © 2020 Published by Elsevier Masson SAS. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Jalandra, Rekha
Yadav, Amit K.
Verma, Damini
Dalal, Nishu
Sharma, Minakshi
Singh, Rajeev
Kumar, Anil
Solanki, Pratima R.
Strategies and perspectives to develop SARS-CoV-2 detection methods and diagnostics
title Strategies and perspectives to develop SARS-CoV-2 detection methods and diagnostics
title_full Strategies and perspectives to develop SARS-CoV-2 detection methods and diagnostics
title_fullStr Strategies and perspectives to develop SARS-CoV-2 detection methods and diagnostics
title_full_unstemmed Strategies and perspectives to develop SARS-CoV-2 detection methods and diagnostics
title_short Strategies and perspectives to develop SARS-CoV-2 detection methods and diagnostics
title_sort strategies and perspectives to develop sars-cov-2 detection methods and diagnostics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303646/
https://www.ncbi.nlm.nih.gov/pubmed/32768943
http://dx.doi.org/10.1016/j.biopha.2020.110446
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