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Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51-depleted ovarian cancer cells

Ovarian cancer is the most lethal gynecological malignancy. Abnormal homologous recombination repair, high level of reactive oxygen species (ROS) and upregulation of antioxidant genes are characteristic features of ovarian cancer. However, the molecular mechanisms governing the redox homeostasis in...

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Detalles Bibliográficos
Autores principales:	Xu, Limei, Wu, Tingting, Lu, Shihua, Hao, Xiaohe, Qin, Junchao, Wang, Jing, Zhang, Xiyu, Liu, Qiao, Kong, Beihua, Gong, Yaoqin, Liu, Zhaojian, Shao, Changshun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303666/ https://www.ncbi.nlm.nih.gov/pubmed/32554304 http://dx.doi.org/10.1016/j.redox.2020.101604

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