Management of central nervous system relapse in a young patient affected by primary mediastinal large B‐cell lymphoma: A case report

In primary mediastinal large B‐cell lymphoma, central nervous system (CNS) relapse is an uncommon event with a dismal prognosis. We report about the successful management of CNS relapse with chemoimmunotherapy according to MATRix (methotrexate, cytarabine, thiotepa, and rituximab) protocol followed...

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Detalles Bibliográficos
Autores principales: Marangon, Miriam, Casadei, Beatrice, Broccoli, Alessandro, Argnani, Lisa, Cavo, Michele, Zinzani, Pier Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303876/
https://www.ncbi.nlm.nih.gov/pubmed/32577237
http://dx.doi.org/10.1002/ccr3.2706
Descripción
Sumario:In primary mediastinal large B‐cell lymphoma, central nervous system (CNS) relapse is an uncommon event with a dismal prognosis. We report about the successful management of CNS relapse with chemoimmunotherapy according to MATRix (methotrexate, cytarabine, thiotepa, and rituximab) protocol followed by autologous stem cell transplant.

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