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Implementing sequence-based antigenic distance calculation into immunological shape space model
BACKGROUND: In 2009, a novel influenza vaccine was distributed worldwide to combat the H1N1 influenza “swine flu” pandemic. However, antibodies induced by the vaccine display differences in their specificity and cross-reactivity dependent on pre-existing immunity. Here, we present a computational mo...
Autores principales: | Anderson, Christopher S., Sangster, Mark Y., Yang, Hongmei, Mariani, Thomas J., Chaudhury, Sidhartha, Topham, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303933/ https://www.ncbi.nlm.nih.gov/pubmed/32560624 http://dx.doi.org/10.1186/s12859-020-03594-3 |
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