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The HSV-1 ubiquitin ligase ICP0: Modifying the cellular proteome to promote infection

Herpes simplex virus 1 (HSV-1) hijacks ubiquitination machinery to modify the cellular proteome to create an environment permissive for virus replication. HSV-1 encodes its own RING-finger E3 ubiquitin (Ub) ligase, Infected Cell Protein 0 (ICP0), that directly interfaces with component proteins of t...

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Detalles Bibliográficos
Autores principales: Rodríguez, Milagros Collados, Dybas, Joseph M., Hughes, Joseph, Weitzman, Matthew D., Boutell, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303953/
https://www.ncbi.nlm.nih.gov/pubmed/32416261
http://dx.doi.org/10.1016/j.virusres.2020.198015

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