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Simulation of Neurotransmitter Flow in Three Dimensional Model of Presynaptic Bouton
In this paper a geometrical model for simulation of the nerve impulses inside the presynaptic bouton is designed. The neurotransmitter flow is described by using partial differential equation with nonlinear term. The bouton is modeled as a distorted geosphere and the mitochondrion inside it as a hig...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304010/ http://dx.doi.org/10.1007/978-3-030-50420-5_10 |
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author | Bielecki, Andrzej Gierdziewicz, Maciej |
author_facet | Bielecki, Andrzej Gierdziewicz, Maciej |
author_sort | Bielecki, Andrzej |
collection | PubMed |
description | In this paper a geometrical model for simulation of the nerve impulses inside the presynaptic bouton is designed. The neurotransmitter flow is described by using partial differential equation with nonlinear term. The bouton is modeled as a distorted geosphere and the mitochondrion inside it as a highly modified cuboid. The quality of the mesh elements is examined. The changes of the amount of neurotransmitter during exocytosis are simulated. |
format | Online Article Text |
id | pubmed-7304010 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
record_format | MEDLINE/PubMed |
spelling | pubmed-73040102020-06-19 Simulation of Neurotransmitter Flow in Three Dimensional Model of Presynaptic Bouton Bielecki, Andrzej Gierdziewicz, Maciej Computational Science – ICCS 2020 Article In this paper a geometrical model for simulation of the nerve impulses inside the presynaptic bouton is designed. The neurotransmitter flow is described by using partial differential equation with nonlinear term. The bouton is modeled as a distorted geosphere and the mitochondrion inside it as a highly modified cuboid. The quality of the mesh elements is examined. The changes of the amount of neurotransmitter during exocytosis are simulated. 2020-05-22 /pmc/articles/PMC7304010/ http://dx.doi.org/10.1007/978-3-030-50420-5_10 Text en © Springer Nature Switzerland AG 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Bielecki, Andrzej Gierdziewicz, Maciej Simulation of Neurotransmitter Flow in Three Dimensional Model of Presynaptic Bouton |
title | Simulation of Neurotransmitter Flow in Three Dimensional Model of Presynaptic Bouton |
title_full | Simulation of Neurotransmitter Flow in Three Dimensional Model of Presynaptic Bouton |
title_fullStr | Simulation of Neurotransmitter Flow in Three Dimensional Model of Presynaptic Bouton |
title_full_unstemmed | Simulation of Neurotransmitter Flow in Three Dimensional Model of Presynaptic Bouton |
title_short | Simulation of Neurotransmitter Flow in Three Dimensional Model of Presynaptic Bouton |
title_sort | simulation of neurotransmitter flow in three dimensional model of presynaptic bouton |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304010/ http://dx.doi.org/10.1007/978-3-030-50420-5_10 |
work_keys_str_mv | AT bieleckiandrzej simulationofneurotransmitterflowinthreedimensionalmodelofpresynapticbouton AT gierdziewiczmaciej simulationofneurotransmitterflowinthreedimensionalmodelofpresynapticbouton |