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Broad Spectrum Deubiquitinase Inhibition Induces Both Apoptosis and Ferroptosis in Cancer Cells

Proteasomal deubiquitinase (DUB) inhibition has been found to be effective in experimental cancer therapy by inducing proteasome inhibition and apoptosis. Ferroptosis is a form of regulated cell death characterized by an iron-dependent lipid peroxidation. Antioxidant enzyme glutathione peroxidase 4...

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Detalles Bibliográficos
Autores principales:	Yang, Li, Chen, Xin, Yang, Qianqian, Chen, Jinghong, Huang, Qingtian, Yao, Leyi, Yan, Ding, Wu, Jiawen, Zhang, Peiquan, Tang, Daolin, Zhong, Nanshan, Liu, Jinbao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304060/ https://www.ncbi.nlm.nih.gov/pubmed/32596160 http://dx.doi.org/10.3389/fonc.2020.00949

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