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β-Turn Mimics by Chemical Ligation

[Image: see text] We report a simple reductive amination protocol to ligate two peptides, while simultaneously installing a β-turn mimic at the ligation junction. This strategy uses commercially available materials, mild chemical conditions, and a chemoselective ligation reaction of unprotected pept...

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Detalles Bibliográficos
Autores principales: Crecente-Garcia, Selma, Neckebroeck, Albane, Clark, J. Stephen, Smith, Brian O., Thomson, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304061/
https://www.ncbi.nlm.nih.gov/pubmed/32406695
http://dx.doi.org/10.1021/acs.orglett.0c01427