Platinum-Triggered Bond-Cleavage of Pentynoyl Amide and N-Propargyl Handles for Drug-Activation

[Image: see text] The ability to create ways to control drug activation at specific tissues while sparing healthy tissues remains a major challenge. The administration of exogenous target-specific triggers offers the potential for traceless release of active drugs on tumor sites from antibody–drug c...

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Detalles Bibliográficos
Autores principales: Oliveira, Bruno L., Stenton, Benjamin J., Unnikrishnan, V. B., de Almeida, Cátia Rebelo, Conde, João, Negrão, Magda, Schneider, Felipe S. S., Cordeiro, Carlos, Ferreira, Miguel Godinho, Caramori, Giovanni F., Domingos, Josiel B., Fior, Rita, Bernardes, Gonçalo J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304066/
https://www.ncbi.nlm.nih.gov/pubmed/32456416
http://dx.doi.org/10.1021/jacs.0c01622

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