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Nutrition in alcohol-related liver disease: Physiopathology and management
Malnutrition encompassing both macro- and micro-nutrient deficiency, remains one of the most frequent complications of alcohol-related liver disease (ArLD). Protein-energy malnutrition can cause significant complications including sarcopenia, frailty and immunodepression in cirrhotic patients. Malnu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304106/ https://www.ncbi.nlm.nih.gov/pubmed/32587439 http://dx.doi.org/10.3748/wjg.v26.i22.2916 |
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author | Kamran, Umair Towey, Jennifer Khanna, Amardeep Chauhan, Abhishek Rajoriya, Neil Holt, Andrew |
author_facet | Kamran, Umair Towey, Jennifer Khanna, Amardeep Chauhan, Abhishek Rajoriya, Neil Holt, Andrew |
author_sort | Kamran, Umair |
collection | PubMed |
description | Malnutrition encompassing both macro- and micro-nutrient deficiency, remains one of the most frequent complications of alcohol-related liver disease (ArLD). Protein-energy malnutrition can cause significant complications including sarcopenia, frailty and immunodepression in cirrhotic patients. Malnutrition reduces patient’s survival and negatively affects the quality of life of individuals with ArLD. Moreover, nutritional deficit increases the likelihood of hepatic decompensation in cirrhosis. Prompt recognition of at-risk individuals, early diagnosis and treatment of malnutrition remains a key component of ArLD management. In this review, we describe the pathophysiology of malnutrition in ArLD, review the screening tools available for nutritional assessment and discuss nutritional management strategies relevant to the different stages of ArLD, ranging from acute alcoholic hepatitis through to decompensated end stage liver disease. |
format | Online Article Text |
id | pubmed-7304106 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-73041062020-06-24 Nutrition in alcohol-related liver disease: Physiopathology and management Kamran, Umair Towey, Jennifer Khanna, Amardeep Chauhan, Abhishek Rajoriya, Neil Holt, Andrew World J Gastroenterol Review Malnutrition encompassing both macro- and micro-nutrient deficiency, remains one of the most frequent complications of alcohol-related liver disease (ArLD). Protein-energy malnutrition can cause significant complications including sarcopenia, frailty and immunodepression in cirrhotic patients. Malnutrition reduces patient’s survival and negatively affects the quality of life of individuals with ArLD. Moreover, nutritional deficit increases the likelihood of hepatic decompensation in cirrhosis. Prompt recognition of at-risk individuals, early diagnosis and treatment of malnutrition remains a key component of ArLD management. In this review, we describe the pathophysiology of malnutrition in ArLD, review the screening tools available for nutritional assessment and discuss nutritional management strategies relevant to the different stages of ArLD, ranging from acute alcoholic hepatitis through to decompensated end stage liver disease. Baishideng Publishing Group Inc 2020-06-14 2020-06-14 /pmc/articles/PMC7304106/ /pubmed/32587439 http://dx.doi.org/10.3748/wjg.v26.i22.2916 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Review Kamran, Umair Towey, Jennifer Khanna, Amardeep Chauhan, Abhishek Rajoriya, Neil Holt, Andrew Nutrition in alcohol-related liver disease: Physiopathology and management |
title | Nutrition in alcohol-related liver disease: Physiopathology and management |
title_full | Nutrition in alcohol-related liver disease: Physiopathology and management |
title_fullStr | Nutrition in alcohol-related liver disease: Physiopathology and management |
title_full_unstemmed | Nutrition in alcohol-related liver disease: Physiopathology and management |
title_short | Nutrition in alcohol-related liver disease: Physiopathology and management |
title_sort | nutrition in alcohol-related liver disease: physiopathology and management |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304106/ https://www.ncbi.nlm.nih.gov/pubmed/32587439 http://dx.doi.org/10.3748/wjg.v26.i22.2916 |
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