Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation

BACKGROUND: Ischemic stroke is a devastating disease without a cure. The available treatments for ischemic stroke, thrombolysis by tissue plasminogen activator, and thrombectomy are suitable only to a fraction of patients and thus novel therapeutic approaches are urgently needed. The neuroinflammato...

Descripción completa

Detalles Bibliográficos
Autores principales: Kolosowska, Natalia, Gotkiewicz, Maria, Dhungana, Hiramani, Giudice, Luca, Giugno, Rosalba, Box, Daphne, Huuskonen, Mikko T., Korhonen, Paula, Scoyni, Flavia, Kanninen, Katja M., Ylä-Herttuala, Seppo, Turunen, Tiia A., Turunen, Mikko P., Koistinaho, Jari, Malm, Tarja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304130/
https://www.ncbi.nlm.nih.gov/pubmed/32560730
http://dx.doi.org/10.1186/s12974-020-01870-w

Ejemplares similares

Ejemplares similares