Cargando…

Cognition and epilepsy: Cognitive screening test

Cognitive deficits often occur in people with epilepsy (PWE). However, in Brazil, PWE might not undergo neurocognitive evaluation due to the low number of validated tests available and lack of multidisciplinary teams in general epilepsy outpatient clinics. OBJECTIVE: To correlate Brief Cognitive Bat...

Descripción completa

Detalles Bibliográficos
Autores principales: Tedrus, Glória Maria Almeida Souza, Passos, Maria Lina Giacomino Almeida, Vargas, Letícia Muniz, Menezes, Larissa Estela Ferreira Jacó
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Neurologia Cognitiva e do Comportamento 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304275/
https://www.ncbi.nlm.nih.gov/pubmed/32595889
http://dx.doi.org/10.1590/1980-57642020dn14-020013
_version_ 1783548233878863872
author Tedrus, Glória Maria Almeida Souza
Passos, Maria Lina Giacomino Almeida
Vargas, Letícia Muniz
Menezes, Larissa Estela Ferreira Jacó
author_facet Tedrus, Glória Maria Almeida Souza
Passos, Maria Lina Giacomino Almeida
Vargas, Letícia Muniz
Menezes, Larissa Estela Ferreira Jacó
author_sort Tedrus, Glória Maria Almeida Souza
collection PubMed
description Cognitive deficits often occur in people with epilepsy (PWE). However, in Brazil, PWE might not undergo neurocognitive evaluation due to the low number of validated tests available and lack of multidisciplinary teams in general epilepsy outpatient clinics. OBJECTIVE: To correlate Brief Cognitive Battery-Edu (BCB-Edu) scores with epilepsy characteristics of 371 PWE. METHODS: Clinical and cognitive assessment (MMSE, BCB-Edu) of 371 PWE aged >18 years was performed. The clinical aspects of epilepsy were correlated with BCB-Edu data. Cognitive data of PWE were compared against those of 95 healthy individuals (NC), with p-<0.05. RESULTS: People with epilepsy had lower cognitive performance than individuals in the NC group. Cognitive aspects also differed according to epilepsy characteristics. Predictive factors for impairment in multiple cognitive domains were age and use of more than one antiepileptic drug (logistic regression; R(2) Nagelkerke=0.135). CONCLUSION: Worse cognitive performance was found in PWE on different domains. There was a relationship between cognitive impairment and the aspects of epilepsy. BCB-Edu proved to be effective as a cognitive assessment screening test for epilepsy in adults.
format Online
Article
Text
id pubmed-7304275
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Associação de Neurologia Cognitiva e do Comportamento
record_format MEDLINE/PubMed
spelling pubmed-73042752020-06-26 Cognition and epilepsy: Cognitive screening test Tedrus, Glória Maria Almeida Souza Passos, Maria Lina Giacomino Almeida Vargas, Letícia Muniz Menezes, Larissa Estela Ferreira Jacó Dement Neuropsychol Original Article Cognitive deficits often occur in people with epilepsy (PWE). However, in Brazil, PWE might not undergo neurocognitive evaluation due to the low number of validated tests available and lack of multidisciplinary teams in general epilepsy outpatient clinics. OBJECTIVE: To correlate Brief Cognitive Battery-Edu (BCB-Edu) scores with epilepsy characteristics of 371 PWE. METHODS: Clinical and cognitive assessment (MMSE, BCB-Edu) of 371 PWE aged >18 years was performed. The clinical aspects of epilepsy were correlated with BCB-Edu data. Cognitive data of PWE were compared against those of 95 healthy individuals (NC), with p-<0.05. RESULTS: People with epilepsy had lower cognitive performance than individuals in the NC group. Cognitive aspects also differed according to epilepsy characteristics. Predictive factors for impairment in multiple cognitive domains were age and use of more than one antiepileptic drug (logistic regression; R(2) Nagelkerke=0.135). CONCLUSION: Worse cognitive performance was found in PWE on different domains. There was a relationship between cognitive impairment and the aspects of epilepsy. BCB-Edu proved to be effective as a cognitive assessment screening test for epilepsy in adults. Associação de Neurologia Cognitiva e do Comportamento 2020 /pmc/articles/PMC7304275/ /pubmed/32595889 http://dx.doi.org/10.1590/1980-57642020dn14-020013 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Tedrus, Glória Maria Almeida Souza
Passos, Maria Lina Giacomino Almeida
Vargas, Letícia Muniz
Menezes, Larissa Estela Ferreira Jacó
Cognition and epilepsy: Cognitive screening test
title Cognition and epilepsy: Cognitive screening test
title_full Cognition and epilepsy: Cognitive screening test
title_fullStr Cognition and epilepsy: Cognitive screening test
title_full_unstemmed Cognition and epilepsy: Cognitive screening test
title_short Cognition and epilepsy: Cognitive screening test
title_sort cognition and epilepsy: cognitive screening test
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304275/
https://www.ncbi.nlm.nih.gov/pubmed/32595889
http://dx.doi.org/10.1590/1980-57642020dn14-020013
work_keys_str_mv AT tedrusgloriamariaalmeidasouza cognitionandepilepsycognitivescreeningtest
AT passosmarialinagiacominoalmeida cognitionandepilepsycognitivescreeningtest
AT vargasleticiamuniz cognitionandepilepsycognitivescreeningtest
AT menezeslarissaestelaferreirajaco cognitionandepilepsycognitivescreeningtest