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Cognition and epilepsy: Cognitive screening test
Cognitive deficits often occur in people with epilepsy (PWE). However, in Brazil, PWE might not undergo neurocognitive evaluation due to the low number of validated tests available and lack of multidisciplinary teams in general epilepsy outpatient clinics. OBJECTIVE: To correlate Brief Cognitive Bat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação de Neurologia Cognitiva e do Comportamento
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304275/ https://www.ncbi.nlm.nih.gov/pubmed/32595889 http://dx.doi.org/10.1590/1980-57642020dn14-020013 |
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author | Tedrus, Glória Maria Almeida Souza Passos, Maria Lina Giacomino Almeida Vargas, Letícia Muniz Menezes, Larissa Estela Ferreira Jacó |
author_facet | Tedrus, Glória Maria Almeida Souza Passos, Maria Lina Giacomino Almeida Vargas, Letícia Muniz Menezes, Larissa Estela Ferreira Jacó |
author_sort | Tedrus, Glória Maria Almeida Souza |
collection | PubMed |
description | Cognitive deficits often occur in people with epilepsy (PWE). However, in Brazil, PWE might not undergo neurocognitive evaluation due to the low number of validated tests available and lack of multidisciplinary teams in general epilepsy outpatient clinics. OBJECTIVE: To correlate Brief Cognitive Battery-Edu (BCB-Edu) scores with epilepsy characteristics of 371 PWE. METHODS: Clinical and cognitive assessment (MMSE, BCB-Edu) of 371 PWE aged >18 years was performed. The clinical aspects of epilepsy were correlated with BCB-Edu data. Cognitive data of PWE were compared against those of 95 healthy individuals (NC), with p-<0.05. RESULTS: People with epilepsy had lower cognitive performance than individuals in the NC group. Cognitive aspects also differed according to epilepsy characteristics. Predictive factors for impairment in multiple cognitive domains were age and use of more than one antiepileptic drug (logistic regression; R(2) Nagelkerke=0.135). CONCLUSION: Worse cognitive performance was found in PWE on different domains. There was a relationship between cognitive impairment and the aspects of epilepsy. BCB-Edu proved to be effective as a cognitive assessment screening test for epilepsy in adults. |
format | Online Article Text |
id | pubmed-7304275 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Associação de Neurologia Cognitiva e do Comportamento |
record_format | MEDLINE/PubMed |
spelling | pubmed-73042752020-06-26 Cognition and epilepsy: Cognitive screening test Tedrus, Glória Maria Almeida Souza Passos, Maria Lina Giacomino Almeida Vargas, Letícia Muniz Menezes, Larissa Estela Ferreira Jacó Dement Neuropsychol Original Article Cognitive deficits often occur in people with epilepsy (PWE). However, in Brazil, PWE might not undergo neurocognitive evaluation due to the low number of validated tests available and lack of multidisciplinary teams in general epilepsy outpatient clinics. OBJECTIVE: To correlate Brief Cognitive Battery-Edu (BCB-Edu) scores with epilepsy characteristics of 371 PWE. METHODS: Clinical and cognitive assessment (MMSE, BCB-Edu) of 371 PWE aged >18 years was performed. The clinical aspects of epilepsy were correlated with BCB-Edu data. Cognitive data of PWE were compared against those of 95 healthy individuals (NC), with p-<0.05. RESULTS: People with epilepsy had lower cognitive performance than individuals in the NC group. Cognitive aspects also differed according to epilepsy characteristics. Predictive factors for impairment in multiple cognitive domains were age and use of more than one antiepileptic drug (logistic regression; R(2) Nagelkerke=0.135). CONCLUSION: Worse cognitive performance was found in PWE on different domains. There was a relationship between cognitive impairment and the aspects of epilepsy. BCB-Edu proved to be effective as a cognitive assessment screening test for epilepsy in adults. Associação de Neurologia Cognitiva e do Comportamento 2020 /pmc/articles/PMC7304275/ /pubmed/32595889 http://dx.doi.org/10.1590/1980-57642020dn14-020013 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Tedrus, Glória Maria Almeida Souza Passos, Maria Lina Giacomino Almeida Vargas, Letícia Muniz Menezes, Larissa Estela Ferreira Jacó Cognition and epilepsy: Cognitive screening test |
title | Cognition and epilepsy: Cognitive screening test |
title_full | Cognition and epilepsy: Cognitive screening test |
title_fullStr | Cognition and epilepsy: Cognitive screening test |
title_full_unstemmed | Cognition and epilepsy: Cognitive screening test |
title_short | Cognition and epilepsy: Cognitive screening test |
title_sort | cognition and epilepsy: cognitive screening test |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304275/ https://www.ncbi.nlm.nih.gov/pubmed/32595889 http://dx.doi.org/10.1590/1980-57642020dn14-020013 |
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