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Gene silencing of HIF-2α disrupts glioblastoma stem cell phenotype

Aim: Improved treatment strategies are desperately needed for eradicating cancer stem cells (CSCs), which drive malignancy and recurrence in glioblastoma multiforme. Hypoxic regions within the tumor microenvironment help maintain and promote the proliferation of CSCs. Here, we explored the effects o...

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Detalles Bibliográficos
Autores principales:	Nusblat, Leora M., Tanna, Shaili, Roth, Charles M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	OAE Publishing Inc. 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304423/ https://www.ncbi.nlm.nih.gov/pubmed/32566921 http://dx.doi.org/10.20517/cdr.2019.96

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