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Profiling Glucose-Stimulated and M3 Receptor-Activated Insulin Secretion Dynamics from Islets of Langerhans Using an Extended-Lifetime Fluorescence Dye

[Image: see text] Pulsatile insulin from pancreatic islets is crucial for glucose homeostasis, but the mechanism behind coordinated pulsatility is still under investigation. One hypothesis suggests that cholinergic stimulation of islets by pancreatic ganglia resets these endocrine units, producing s...

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Detalles Bibliográficos
Autores principales: Adablah, Joel E., Wang, Yao, Donohue, Matthew, Roper, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304439/
https://www.ncbi.nlm.nih.gov/pubmed/32429660
http://dx.doi.org/10.1021/acs.analchem.0c01226