The CNS-specific proteoglycan, brevican, and its ADAMTS4-cleaved fragment show differential serological levels in Alzheimer’s disease, other types of dementia and non-demented controls: A cross-sectional study

Evidence indicate that the brain-specific protein, brevican, is proteolytically cleaved during neurodegeneration, hence positioning fragments of brevican as potential blood biomarkers of neurodegenerative diseases, such as dementia. We aimed to develop two assays capable of detecting the brevican N-...

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Detalles Bibliográficos
Autores principales: Jonesco, Ditte S., Karsdal, Morten A., Henriksen, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304580/
https://www.ncbi.nlm.nih.gov/pubmed/32559242
http://dx.doi.org/10.1371/journal.pone.0234632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304580/
https://www.ncbi.nlm.nih.gov/pubmed/32559242
http://dx.doi.org/10.1371/journal.pone.0234632

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