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Assessing Site-Specific Enhancements Imparted by Hyperpolarized Water in Folded and Unfolded Proteins by 2D HMQC NMR

[Image: see text] Hyperpolarized water can be a valuable aid in protein NMR, leading to amide group (1)H polarizations that are orders of magnitude larger than their thermal counterparts. Suitable procedures can exploit this to deliver 2D (1)H–(15)N correlations with good resolution and enhanced sen...

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Detalles Bibliográficos
Autores principales: Szekely, Or, Olsen, Gregory Lars, Novakovic, Mihajlo, Rosenzweig, Rina, Frydman, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304870/
https://www.ncbi.nlm.nih.gov/pubmed/32338002
http://dx.doi.org/10.1021/jacs.0c00807