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MicroRNA-21/PDCD4 Proapoptotic Signaling From Circulating CD34(+) Cells to Vascular Endothelial Cells: A Potential Contributor to Adverse Cardiovascular Outcomes in Patients With Critical Limb Ischemia
OBJECTIVE: In patients with type 2 diabetes (T2D) and critical limb ischemia (CLI), migration of circulating CD34(+) cells predicted cardiovascular mortality at 18 months after revascularization. This study aimed to provide long-term validation and mechanistic understanding of the biomarker. RESEARC...
Autores principales: | Spinetti, Gaia, Sangalli, Elena, Tagliabue, Elena, Maselli, Davide, Colpani, Ornella, Ferland-McCollough, David, Carnelli, Franco, Orlando, Patrizia, Paccagnella, Agostino, Furlan, Anna, Stefani, Piero Maria, Sambado, Luisa, Sambataro, Maria, Madeddu, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305013/ https://www.ncbi.nlm.nih.gov/pubmed/32358022 http://dx.doi.org/10.2337/dc19-2227 |
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