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MicroRNA-21/PDCD4 Proapoptotic Signaling From Circulating CD34(+) Cells to Vascular Endothelial Cells: A Potential Contributor to Adverse Cardiovascular Outcomes in Patients With Critical Limb Ischemia

OBJECTIVE: In patients with type 2 diabetes (T2D) and critical limb ischemia (CLI), migration of circulating CD34(+) cells predicted cardiovascular mortality at 18 months after revascularization. This study aimed to provide long-term validation and mechanistic understanding of the biomarker. RESEARC...

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Detalles Bibliográficos
Autores principales: Spinetti, Gaia, Sangalli, Elena, Tagliabue, Elena, Maselli, Davide, Colpani, Ornella, Ferland-McCollough, David, Carnelli, Franco, Orlando, Patrizia, Paccagnella, Agostino, Furlan, Anna, Stefani, Piero Maria, Sambado, Luisa, Sambataro, Maria, Madeddu, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305013/
https://www.ncbi.nlm.nih.gov/pubmed/32358022
http://dx.doi.org/10.2337/dc19-2227

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