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Utility of Inflammatory Markers in Detection of Perioperative Morbidity After Laparoscopic Sleeve Gastrectomy, Laparoscopic Roux-en-Y Gastric Bypass, and One-Anastomosis Gastric Bypass—Multicenter Study

BACKGROUND: The most commonly performed bariatric operations are laparoscopic sleeve gastrectomy (LSG) and bypass surgeries (laparoscopic one-anastomosis gastric bypass (OAGB) and laparoscopic Roux-en-Y gastric bypass (LRYGB)), and predicting perioperative morbidity is crucial for early, safe patien...

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Autores principales: Wysocki, Michał, Małczak, Piotr, Wierdak, Mateusz, Walędziak, Maciej, Hady, Hady Razak, Diemieszczyk, Inna, Proczko-Stepaniak, Monika, Szymański, Michał, Dowgiałło-Wnukiewicz, Natalia, Szeliga, Jacek, Pędziwiatr, Michał, Major, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305064/
https://www.ncbi.nlm.nih.gov/pubmed/32347517
http://dx.doi.org/10.1007/s11695-020-04636-8
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author Wysocki, Michał
Małczak, Piotr
Wierdak, Mateusz
Walędziak, Maciej
Hady, Hady Razak
Diemieszczyk, Inna
Proczko-Stepaniak, Monika
Szymański, Michał
Dowgiałło-Wnukiewicz, Natalia
Szeliga, Jacek
Pędziwiatr, Michał
Major, Piotr
author_facet Wysocki, Michał
Małczak, Piotr
Wierdak, Mateusz
Walędziak, Maciej
Hady, Hady Razak
Diemieszczyk, Inna
Proczko-Stepaniak, Monika
Szymański, Michał
Dowgiałło-Wnukiewicz, Natalia
Szeliga, Jacek
Pędziwiatr, Michał
Major, Piotr
author_sort Wysocki, Michał
collection PubMed
description BACKGROUND: The most commonly performed bariatric operations are laparoscopic sleeve gastrectomy (LSG) and bypass surgeries (laparoscopic one-anastomosis gastric bypass (OAGB) and laparoscopic Roux-en-Y gastric bypass (LRYGB)), and predicting perioperative morbidity is crucial for early, safe patient discharge. We aimed to determine whether C-reactive protein (CRP) and white blood count (WBC) measured on the first postoperative day predicts perioperative morbidity in the first 30-days after LSG and bypass surgeries. METHODS: We retrospectively analyzed data for 1400 patients who underwent bariatric surgery in seven bariatric centers from 2014 to 2018. Patients were divided into a complicated group (patients with postoperative complications) and a non-complicated group. We also performed separate analyses for LSG and bypass surgeries. RESULTS: Patients were 929 women (66%) and 471 men (34%) with a median age of 42 years (range, 35–51 years); 1192 patients underwent LSG (85%), 120 underwent LRYGB (9%), and 80 underwent OAGB (6%). We performed ROC analyses to set cut-off points, followed by multivariate logistic regressions. CRP > 33.32 mg/L increased the odds ratio (OR) of perioperative complications after LSG 2.27 times, while WBC > 12.15 × 10(3)/μL on postoperative day 1 was associated with a 3.34-times greater or of developing complications. WBC > 13.78 × 10(3)/μL was associated with a 13.34-times higher or of perioperative morbidity in patients undergoing bypass surgeries. CONCLUSION: Even slightly elevated CRP and WBC on postoperative day 1 should alert surgeons to the potential risk of perioperative morbidity.
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spelling pubmed-73050642020-06-22 Utility of Inflammatory Markers in Detection of Perioperative Morbidity After Laparoscopic Sleeve Gastrectomy, Laparoscopic Roux-en-Y Gastric Bypass, and One-Anastomosis Gastric Bypass—Multicenter Study Wysocki, Michał Małczak, Piotr Wierdak, Mateusz Walędziak, Maciej Hady, Hady Razak Diemieszczyk, Inna Proczko-Stepaniak, Monika Szymański, Michał Dowgiałło-Wnukiewicz, Natalia Szeliga, Jacek Pędziwiatr, Michał Major, Piotr Obes Surg Original Contributions BACKGROUND: The most commonly performed bariatric operations are laparoscopic sleeve gastrectomy (LSG) and bypass surgeries (laparoscopic one-anastomosis gastric bypass (OAGB) and laparoscopic Roux-en-Y gastric bypass (LRYGB)), and predicting perioperative morbidity is crucial for early, safe patient discharge. We aimed to determine whether C-reactive protein (CRP) and white blood count (WBC) measured on the first postoperative day predicts perioperative morbidity in the first 30-days after LSG and bypass surgeries. METHODS: We retrospectively analyzed data for 1400 patients who underwent bariatric surgery in seven bariatric centers from 2014 to 2018. Patients were divided into a complicated group (patients with postoperative complications) and a non-complicated group. We also performed separate analyses for LSG and bypass surgeries. RESULTS: Patients were 929 women (66%) and 471 men (34%) with a median age of 42 years (range, 35–51 years); 1192 patients underwent LSG (85%), 120 underwent LRYGB (9%), and 80 underwent OAGB (6%). We performed ROC analyses to set cut-off points, followed by multivariate logistic regressions. CRP > 33.32 mg/L increased the odds ratio (OR) of perioperative complications after LSG 2.27 times, while WBC > 12.15 × 10(3)/μL on postoperative day 1 was associated with a 3.34-times greater or of developing complications. WBC > 13.78 × 10(3)/μL was associated with a 13.34-times higher or of perioperative morbidity in patients undergoing bypass surgeries. CONCLUSION: Even slightly elevated CRP and WBC on postoperative day 1 should alert surgeons to the potential risk of perioperative morbidity. Springer US 2020-04-28 2020 /pmc/articles/PMC7305064/ /pubmed/32347517 http://dx.doi.org/10.1007/s11695-020-04636-8 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Contributions
Wysocki, Michał
Małczak, Piotr
Wierdak, Mateusz
Walędziak, Maciej
Hady, Hady Razak
Diemieszczyk, Inna
Proczko-Stepaniak, Monika
Szymański, Michał
Dowgiałło-Wnukiewicz, Natalia
Szeliga, Jacek
Pędziwiatr, Michał
Major, Piotr
Utility of Inflammatory Markers in Detection of Perioperative Morbidity After Laparoscopic Sleeve Gastrectomy, Laparoscopic Roux-en-Y Gastric Bypass, and One-Anastomosis Gastric Bypass—Multicenter Study
title Utility of Inflammatory Markers in Detection of Perioperative Morbidity After Laparoscopic Sleeve Gastrectomy, Laparoscopic Roux-en-Y Gastric Bypass, and One-Anastomosis Gastric Bypass—Multicenter Study
title_full Utility of Inflammatory Markers in Detection of Perioperative Morbidity After Laparoscopic Sleeve Gastrectomy, Laparoscopic Roux-en-Y Gastric Bypass, and One-Anastomosis Gastric Bypass—Multicenter Study
title_fullStr Utility of Inflammatory Markers in Detection of Perioperative Morbidity After Laparoscopic Sleeve Gastrectomy, Laparoscopic Roux-en-Y Gastric Bypass, and One-Anastomosis Gastric Bypass—Multicenter Study
title_full_unstemmed Utility of Inflammatory Markers in Detection of Perioperative Morbidity After Laparoscopic Sleeve Gastrectomy, Laparoscopic Roux-en-Y Gastric Bypass, and One-Anastomosis Gastric Bypass—Multicenter Study
title_short Utility of Inflammatory Markers in Detection of Perioperative Morbidity After Laparoscopic Sleeve Gastrectomy, Laparoscopic Roux-en-Y Gastric Bypass, and One-Anastomosis Gastric Bypass—Multicenter Study
title_sort utility of inflammatory markers in detection of perioperative morbidity after laparoscopic sleeve gastrectomy, laparoscopic roux-en-y gastric bypass, and one-anastomosis gastric bypass—multicenter study
topic Original Contributions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305064/
https://www.ncbi.nlm.nih.gov/pubmed/32347517
http://dx.doi.org/10.1007/s11695-020-04636-8
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