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Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits

Synthetic biology has focused on engineering genetic modules that operate orthogonally from the host cells. A synthetic biological module, however, can be designed to reprogram the host proteome, which in turn enhances the function of the synthetic module. Here, we apply this holistic synthetic biol...

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Detalles Bibliográficos
Autores principales: Contreras-Llano, Luis E., Meyer, Conary, Liu, Yao, Sarker, Mridul, Lim, Sierin, Longo, Marjorie L., Tan, Cheemeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305103/
https://www.ncbi.nlm.nih.gov/pubmed/32561745
http://dx.doi.org/10.1038/s41467-020-16900-7