Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

Proximity proteomics has greatly advanced the analysis of native protein complexes and subcellular structures in culture, but has not been amenable to study development and disease in vivo. Here, we have generated a knock-in mouse with the biotin ligase (BioID) inserted at titin’s Z-disc region to i...

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Detalles Bibliográficos
Autores principales: Rudolph, Franziska, Fink, Claudia, Hüttemeister, Judith, Kirchner, Marieluise, Radke, Michael H., Lopez Carballo, Jacobo, Wagner, Eva, Kohl, Tobias, Lehnart, Stephan E., Mertins, Philipp, Gotthardt, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305127/
https://www.ncbi.nlm.nih.gov/pubmed/32561764
http://dx.doi.org/10.1038/s41467-020-16929-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305127/
https://www.ncbi.nlm.nih.gov/pubmed/32561764
http://dx.doi.org/10.1038/s41467-020-16929-8

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