Structural basis of host protein hijacking in human T-cell leukemia virus integration

Integration of the reverse-transcribed viral DNA into host chromosomes is a critical step in the life-cycle of retroviruses, including an oncogenic delta(δ)-retrovirus human T-cell leukemia virus type-1 (HTLV-1). Retroviral integrase forms a higher order nucleoprotein assembly (intasome) to catalyze...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhatt, Veer, Shi, Ke, Salamango, Daniel J., Moeller, Nicholas H., Pandey, Krishan K., Bera, Sibes, Bohl, Heather O., Kurniawan, Fredy, Orellana, Kayo, Zhang, Wei, Grandgenett, Duane P., Harris, Reuben S., Sundborger-Lunna, Anna C., Aihara, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305164/
https://www.ncbi.nlm.nih.gov/pubmed/32561747
http://dx.doi.org/10.1038/s41467-020-16963-6

Ejemplares similares

Ejemplares similares