Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity

Mouse embryos acquire global DNA methylation of their genome during implantation. However the exact roles of DNA methyltransferases (DNMTs) in embryos have not been studied comprehensively. Here we systematically analyze the consequences of genetic inactivation of Dnmt1, Dnmt3a and Dnmt3b on the met...

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Detalles Bibliográficos
Autores principales: Dahlet, Thomas, Argüeso Lleida, Andrea, Al Adhami, Hala, Dumas, Michael, Bender, Ambre, Ngondo, Richard P., Tanguy, Manon, Vallet, Judith, Auclair, Ghislain, Bardet, Anaïs F., Weber, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305168/
https://www.ncbi.nlm.nih.gov/pubmed/32561758
http://dx.doi.org/10.1038/s41467-020-16919-w

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