High flavivirus structural plasticity demonstrated by a non-spherical morphological variant

Previous flavivirus (dengue and Zika viruses) studies showed largely spherical particles either with smooth or bumpy surfaces. Here, we demonstrate flavivirus particles have high structural plasticity by the induction of a non-spherical morphology at elevated temperatures: the club-shaped particle (...

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Detalles Bibliográficos
Autores principales: Morrone, Seamus R., Chew, Valerie S. Y., Lim, Xin-Ni, Ng, Thiam-Seng, Kostyuchenko, Victor A., Zhang, Shuijun, Wirawan, Melissa, Chew, Pau-Ling, Lee, Jaime, Tan, Joanne L., Wang, Jiaqi, Tan, Ter Yong, Shi, Jian, Screaton, Gavin, Morais, Marc C., Lok, Shee-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305169/
https://www.ncbi.nlm.nih.gov/pubmed/32561757
http://dx.doi.org/10.1038/s41467-020-16925-y

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