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Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given?

BACKGROUND: Obesity is a chronic relapsing-remitting disease and a global pandemic, being associated with multiple comorbidities. Laparoscopic adjustable gastric banding (LAGB) is one of the safest surgical procedures used for the treatment of obesity, and even though its popularity has been decreas...

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Autores principales: Leca, Bianca M., Khan, Uzma, Abraham, Jenny, Halder, Louise, Shuttlewood, Emma, Shah, Neha, Ellis, Hugh L., Aylwin, Simon J. B., Barber, Thomas M., Menon, Vinod, Randeva, Harpal S., Dimitriadis, Georgios K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305253/
https://www.ncbi.nlm.nih.gov/pubmed/32304013
http://dx.doi.org/10.1007/s11695-020-04613-1
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author Leca, Bianca M.
Khan, Uzma
Abraham, Jenny
Halder, Louise
Shuttlewood, Emma
Shah, Neha
Ellis, Hugh L.
Aylwin, Simon J. B.
Barber, Thomas M.
Menon, Vinod
Randeva, Harpal S.
Dimitriadis, Georgios K.
author_facet Leca, Bianca M.
Khan, Uzma
Abraham, Jenny
Halder, Louise
Shuttlewood, Emma
Shah, Neha
Ellis, Hugh L.
Aylwin, Simon J. B.
Barber, Thomas M.
Menon, Vinod
Randeva, Harpal S.
Dimitriadis, Georgios K.
author_sort Leca, Bianca M.
collection PubMed
description BACKGROUND: Obesity is a chronic relapsing-remitting disease and a global pandemic, being associated with multiple comorbidities. Laparoscopic adjustable gastric banding (LAGB) is one of the safest surgical procedures used for the treatment of obesity, and even though its popularity has been decreasing over time, it still remains an option for a certain group of patients, producing considerable weight loss and improvement in obesity-associated comorbidities. METHODS: The aim of this study was to evaluate the impact of weight loss following LAGB on obesity-associated comorbidities, and to identify factors that could predict better response to surgery, and patient sub-groups exhibiting greatest benefit. A total of 99 severely obese patients (81.2% women, mean age 44.19 ± 10.94 years, mean body mass index (BMI) 51.84 ± 8.77 kg/m(2)) underwent LAGB in a single institution. Results obtained 1, 2, and 5 years postoperatively were compared with the pre-operative values using SPPS software version 20. RESULTS: A significant drop in BMI was recorded throughout the follow-up period, as well as in A1c and triglycerides, with greatest improvement seen 2 years after surgery (51.8 ± 8.7 kg/m(2) vs 42.3 ± 9.2 kg/m(2), p < 0.05, 55.5 ± 19.1 mmol/mol vs 45.8 ± 13.7 mmol/mol, p < 0.05, and 2.2 ± 1.7 mmol/l vs 1.5 ± 0.6 mmol/l). Better outcomes were seen in younger patients, with lower duration of diabetes before surgery, and lower pre-operative systolic blood pressure. CONCLUSIONS: Younger age, lower degree of obesity, and lower severity of comorbidities at the time of surgery can be important predictors of successful weight loss, making this group of patients the ideal candidates for LAGB.
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spelling pubmed-73052532020-06-22 Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given? Leca, Bianca M. Khan, Uzma Abraham, Jenny Halder, Louise Shuttlewood, Emma Shah, Neha Ellis, Hugh L. Aylwin, Simon J. B. Barber, Thomas M. Menon, Vinod Randeva, Harpal S. Dimitriadis, Georgios K. Obes Surg Original Contributions BACKGROUND: Obesity is a chronic relapsing-remitting disease and a global pandemic, being associated with multiple comorbidities. Laparoscopic adjustable gastric banding (LAGB) is one of the safest surgical procedures used for the treatment of obesity, and even though its popularity has been decreasing over time, it still remains an option for a certain group of patients, producing considerable weight loss and improvement in obesity-associated comorbidities. METHODS: The aim of this study was to evaluate the impact of weight loss following LAGB on obesity-associated comorbidities, and to identify factors that could predict better response to surgery, and patient sub-groups exhibiting greatest benefit. A total of 99 severely obese patients (81.2% women, mean age 44.19 ± 10.94 years, mean body mass index (BMI) 51.84 ± 8.77 kg/m(2)) underwent LAGB in a single institution. Results obtained 1, 2, and 5 years postoperatively were compared with the pre-operative values using SPPS software version 20. RESULTS: A significant drop in BMI was recorded throughout the follow-up period, as well as in A1c and triglycerides, with greatest improvement seen 2 years after surgery (51.8 ± 8.7 kg/m(2) vs 42.3 ± 9.2 kg/m(2), p < 0.05, 55.5 ± 19.1 mmol/mol vs 45.8 ± 13.7 mmol/mol, p < 0.05, and 2.2 ± 1.7 mmol/l vs 1.5 ± 0.6 mmol/l). Better outcomes were seen in younger patients, with lower duration of diabetes before surgery, and lower pre-operative systolic blood pressure. CONCLUSIONS: Younger age, lower degree of obesity, and lower severity of comorbidities at the time of surgery can be important predictors of successful weight loss, making this group of patients the ideal candidates for LAGB. Springer US 2020-04-18 2020 /pmc/articles/PMC7305253/ /pubmed/32304013 http://dx.doi.org/10.1007/s11695-020-04613-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Contributions
Leca, Bianca M.
Khan, Uzma
Abraham, Jenny
Halder, Louise
Shuttlewood, Emma
Shah, Neha
Ellis, Hugh L.
Aylwin, Simon J. B.
Barber, Thomas M.
Menon, Vinod
Randeva, Harpal S.
Dimitriadis, Georgios K.
Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given?
title Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given?
title_full Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given?
title_fullStr Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given?
title_full_unstemmed Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given?
title_short Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given?
title_sort laparoscopic adjustable gastric banding—should a second chance be given?
topic Original Contributions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305253/
https://www.ncbi.nlm.nih.gov/pubmed/32304013
http://dx.doi.org/10.1007/s11695-020-04613-1
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