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SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer

SIRT7, a sirtuin family member implicated in aging and disease, is a regulator of metabolism and stress responses. It remains elusive how human somatic stem cell populations might be impacted by SIRT7. Here, we found that SIRT7 expression declines during human mesenchymal stem cell (hMSC) aging and...

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Detalles Bibliográficos
Autores principales:	Bi, Shijia, Liu, Zunpeng, Wu, Zeming, Wang, Zehua, Liu, Xiaoqian, Wang, Si, Ren, Jie, Yao, Yan, Zhang, Weiqi, Song, Moshi, Liu, Guang-Hui, Qu, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305295/ https://www.ncbi.nlm.nih.gov/pubmed/32504224 http://dx.doi.org/10.1007/s13238-020-00728-4

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