Talin dissociates from RIAM and associates to vinculin sequentially in response to the actomyosin force

Cells reinforce adhesion strength and cytoskeleton anchoring in response to the actomyosin force. The mechanical stretching of talin, which exposes cryptic vinculin-binding sites, triggers this process. The binding of RIAM to talin could regulate this mechanism. However, the mechanosensitivity of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Vigouroux, Clémence, Henriot, Véronique, Le Clainche, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305319/
https://www.ncbi.nlm.nih.gov/pubmed/32561773
http://dx.doi.org/10.1038/s41467-020-16922-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305319/
https://www.ncbi.nlm.nih.gov/pubmed/32561773
http://dx.doi.org/10.1038/s41467-020-16922-1

Ejemplares similares