Cargando…
Confirmed E-cigarette or vaping product use associated lung injury (EVALI) with lung biopsy; A case report and literature review
BACKGROUND: E-cigarette or vaping has become an increasingly popular alternative to smoking tobacco. In September 2019 multiple cases of confirmed E-cigarette or vaping product use associated lung injury were published. However, there is limited knowledge regarding the pathologic mechanism of this c...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305409/ https://www.ncbi.nlm.nih.gov/pubmed/32577363 http://dx.doi.org/10.1016/j.rmcr.2020.101122 |
_version_ | 1783548455064436736 |
---|---|
author | Cedano, Jorge Sah, Anuraag Cedeno-Mendoza, Ricardo Fish, Heidi Remolina, Carlos |
author_facet | Cedano, Jorge Sah, Anuraag Cedeno-Mendoza, Ricardo Fish, Heidi Remolina, Carlos |
author_sort | Cedano, Jorge |
collection | PubMed |
description | BACKGROUND: E-cigarette or vaping has become an increasingly popular alternative to smoking tobacco. In September 2019 multiple cases of confirmed E-cigarette or vaping product use associated lung injury were published. However, there is limited knowledge regarding the pathologic mechanism of this condition. METHODS: We performed a systematic literature review in PubMed and EMBASE aiming to obtain additional clinical data on confirmed E-cigarette or vaping product use associated lung injury cases with lung biopsy results. With this information we hope to determine whether this condition is related to a histopathological pattern of acute lung injury instead of lipid deposits. RESULTS: Seven articles were reviewed and a total of 27 cases were included. Imaging findings predominantly showed presence of diffuse bilateral ground glass opacities. A majority of patients had complete resolution of the disease. The most common histopathological pattern was organizing pneumonia present in almost half of the patients. Other frequently occurring patterns included diffuse alveolar damage and acute fibrinous pneumonitis; lipoid pneumonia was found in one case. CONCLUSION: The underlying pathophysiological mechanism in E-cigarette or vaping product use associated lung injury is most likely acute lung injury related to direct inhalant-mediated parenchymal inflammation. |
format | Online Article Text |
id | pubmed-7305409 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-73054092020-06-22 Confirmed E-cigarette or vaping product use associated lung injury (EVALI) with lung biopsy; A case report and literature review Cedano, Jorge Sah, Anuraag Cedeno-Mendoza, Ricardo Fish, Heidi Remolina, Carlos Respir Med Case Rep Case Report BACKGROUND: E-cigarette or vaping has become an increasingly popular alternative to smoking tobacco. In September 2019 multiple cases of confirmed E-cigarette or vaping product use associated lung injury were published. However, there is limited knowledge regarding the pathologic mechanism of this condition. METHODS: We performed a systematic literature review in PubMed and EMBASE aiming to obtain additional clinical data on confirmed E-cigarette or vaping product use associated lung injury cases with lung biopsy results. With this information we hope to determine whether this condition is related to a histopathological pattern of acute lung injury instead of lipid deposits. RESULTS: Seven articles were reviewed and a total of 27 cases were included. Imaging findings predominantly showed presence of diffuse bilateral ground glass opacities. A majority of patients had complete resolution of the disease. The most common histopathological pattern was organizing pneumonia present in almost half of the patients. Other frequently occurring patterns included diffuse alveolar damage and acute fibrinous pneumonitis; lipoid pneumonia was found in one case. CONCLUSION: The underlying pathophysiological mechanism in E-cigarette or vaping product use associated lung injury is most likely acute lung injury related to direct inhalant-mediated parenchymal inflammation. Elsevier 2020-06-11 /pmc/articles/PMC7305409/ /pubmed/32577363 http://dx.doi.org/10.1016/j.rmcr.2020.101122 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Cedano, Jorge Sah, Anuraag Cedeno-Mendoza, Ricardo Fish, Heidi Remolina, Carlos Confirmed E-cigarette or vaping product use associated lung injury (EVALI) with lung biopsy; A case report and literature review |
title | Confirmed E-cigarette or vaping product use associated lung injury (EVALI) with lung biopsy; A case report and literature review |
title_full | Confirmed E-cigarette or vaping product use associated lung injury (EVALI) with lung biopsy; A case report and literature review |
title_fullStr | Confirmed E-cigarette or vaping product use associated lung injury (EVALI) with lung biopsy; A case report and literature review |
title_full_unstemmed | Confirmed E-cigarette or vaping product use associated lung injury (EVALI) with lung biopsy; A case report and literature review |
title_short | Confirmed E-cigarette or vaping product use associated lung injury (EVALI) with lung biopsy; A case report and literature review |
title_sort | confirmed e-cigarette or vaping product use associated lung injury (evali) with lung biopsy; a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305409/ https://www.ncbi.nlm.nih.gov/pubmed/32577363 http://dx.doi.org/10.1016/j.rmcr.2020.101122 |
work_keys_str_mv | AT cedanojorge confirmedecigaretteorvapingproductuseassociatedlunginjuryevaliwithlungbiopsyacasereportandliteraturereview AT sahanuraag confirmedecigaretteorvapingproductuseassociatedlunginjuryevaliwithlungbiopsyacasereportandliteraturereview AT cedenomendozaricardo confirmedecigaretteorvapingproductuseassociatedlunginjuryevaliwithlungbiopsyacasereportandliteraturereview AT fishheidi confirmedecigaretteorvapingproductuseassociatedlunginjuryevaliwithlungbiopsyacasereportandliteraturereview AT remolinacarlos confirmedecigaretteorvapingproductuseassociatedlunginjuryevaliwithlungbiopsyacasereportandliteraturereview |