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Quantifying the effects of quarantine using an IBM SEIR model on scalefree networks

The COVID-19 pandemic led several countries to resort to social distancing, the only known way to slow down the spread of the virus and keep the health system under control. Here we use an individual based model (IBM) to study how the duration, start date and intensity of quarantine affect the heigh...

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Detalles Bibliográficos
Autores principales: Marquioni, Vitor M., de Aguiar, Marcus A.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305517/
https://www.ncbi.nlm.nih.gov/pubmed/32834581
http://dx.doi.org/10.1016/j.chaos.2020.109999
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author Marquioni, Vitor M.
de Aguiar, Marcus A.M.
author_facet Marquioni, Vitor M.
de Aguiar, Marcus A.M.
author_sort Marquioni, Vitor M.
collection PubMed
description The COVID-19 pandemic led several countries to resort to social distancing, the only known way to slow down the spread of the virus and keep the health system under control. Here we use an individual based model (IBM) to study how the duration, start date and intensity of quarantine affect the height and position of the peak of the infection curve. We show that stochastic effects, inherent to the model dynamics, lead to variable outcomes for the same set of parameters, making it crucial to compute the probability of each result. To simplify the analysis we divide the outcomes in only two categories, that we call best and worst scenarios. Although long and intense quarantine is the best way to end the epidemic, it is very hard to implement in practice. Here we show that relatively short and intense quarantine periods can also be very effective in flattening the infection curve and even killing the virus, but the likelihood of such outcomes are low. Long quarantines of relatively low intensity, on the other hand, can delay the infection peak and reduce its size considerably with more than 50% probability, being a more effective policy than complete lockdown for short periods.
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spelling pubmed-73055172020-06-22 Quantifying the effects of quarantine using an IBM SEIR model on scalefree networks Marquioni, Vitor M. de Aguiar, Marcus A.M. Chaos Solitons Fractals Article The COVID-19 pandemic led several countries to resort to social distancing, the only known way to slow down the spread of the virus and keep the health system under control. Here we use an individual based model (IBM) to study how the duration, start date and intensity of quarantine affect the height and position of the peak of the infection curve. We show that stochastic effects, inherent to the model dynamics, lead to variable outcomes for the same set of parameters, making it crucial to compute the probability of each result. To simplify the analysis we divide the outcomes in only two categories, that we call best and worst scenarios. Although long and intense quarantine is the best way to end the epidemic, it is very hard to implement in practice. Here we show that relatively short and intense quarantine periods can also be very effective in flattening the infection curve and even killing the virus, but the likelihood of such outcomes are low. Long quarantines of relatively low intensity, on the other hand, can delay the infection peak and reduce its size considerably with more than 50% probability, being a more effective policy than complete lockdown for short periods. Elsevier Ltd. 2020-09 2020-06-20 /pmc/articles/PMC7305517/ /pubmed/32834581 http://dx.doi.org/10.1016/j.chaos.2020.109999 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Marquioni, Vitor M.
de Aguiar, Marcus A.M.
Quantifying the effects of quarantine using an IBM SEIR model on scalefree networks
title Quantifying the effects of quarantine using an IBM SEIR model on scalefree networks
title_full Quantifying the effects of quarantine using an IBM SEIR model on scalefree networks
title_fullStr Quantifying the effects of quarantine using an IBM SEIR model on scalefree networks
title_full_unstemmed Quantifying the effects of quarantine using an IBM SEIR model on scalefree networks
title_short Quantifying the effects of quarantine using an IBM SEIR model on scalefree networks
title_sort quantifying the effects of quarantine using an ibm seir model on scalefree networks
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305517/
https://www.ncbi.nlm.nih.gov/pubmed/32834581
http://dx.doi.org/10.1016/j.chaos.2020.109999
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